A recent study estimates that around 200 million cases of diseases of polio, mumps, rubella, measles, adenovirus, hepatitis A and rabies have been prevented in the U.S. with the help of vaccination from 1963 to 2015.

The study also reveals that about 450,000 deaths have been avoided in the U.S during this period.

The vaccination became widespread in 1963 after the safe production of these vaccines started due to the discovery of the human cell strain. The vaccines produced from these cell strains prevented almost 4.5 billion occurrences of the diseases and also stopped them from coming back in over 10 million people worldwide in 1963.
The Human Cell Strain

In 1962, Leonard Hayflick, co-author of the study, discovered the regular human cell strain. This cell strain enabled the growth of viruses, which are in turn required to manufacture vaccines. Scientists were able to develop vaccines for 10 diseases using the human cell strain.

However, the production of vaccines came to an end leaving millions of people unprotected against several diseases. The vaccines saw an end due to the viral vaccines of monkey cells.

"Given the acknowledged large, positive global health impact of vaccines in general, I was curious what contribution my discovery of WI-38 in 1962 had in saving lives and reducing morbidity, since a large number of viral vaccines in use today are made with my cell strain or its derivatives," said Hayflick.
The Study

Hayflick collaborated with S. Jay Olshansky and conducted the study to discover the sheer number of deaths and diseases prevented by WI-38 till 2015. Olshansky checked with earlier data pertaining to the cases and deaths for each disease that occurred in the U.S. in 1960.

It was the year when vaccines were not available for prevention of the diseases. He made an assumption that the death and disease occurrence rates were constant throughout the year.

To study the number of reports where lives have been saved and the disease prevented, Olshansky multiplied the number of years vaccines have been prevalent by the number of deaths due to the disease.
Findings Of The Study

The study showed that the parents in California feared the use of vaccines. As a result, unvaccinated children suffered from acute measles, causing an outbreak in 2014 and 2015. Olshansky noted that the unvaccinated children did not only pose problems for themselves, but also lowered the herd immunity.

The study estimated that around 1.4 million unvaccinated children under 5 years die each year. Moreover, the researcher noted that anti-vaccine movement in the U.S. is creating a negative environment in the country, due to which vaccination rates for several diseases are as little as 50 percent to 86 percent.

Vaccines offer several life-saving and primary prevention benefits. Additionally, Hayflick asserted that there isn't any medication or public health innovation that can replace the vaccines.

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